Adrenoleukodystrophy is a genetically transferred disease which causes the human body to not be able to breakdown very-long-chain-fatty-acids (VLCFA). This inability to break down these acids eventually leads to myelin deterioration as well as the deterioration of the nervous system. Although there is no cure for this terrible disease, there are a variety of effective treatments.Adrenoleukodystrophy is a sex-linked trait carried on the X-chromosome and is carried by the mother. It is only passed on to male children, and every male child that a carrier mother gives birth to has a fifty-fifty chance of acquiring adrenoleukodystrophy. Adrenoleukodystrophy, more commonly called ALD, affects the nervous system. The inability to break down fatty acids causes demyelination of the nerves in the brain, spinal cord, and other areas of the body. Myelin is the insulating sheath around a nerve, and is broken down during demyelination. Once the myelin disappears, nerves will start to short-circuit and stop working. Symptoms can include seizures, tantrums, and mood-swings. ALD generally occurs in one of three main forms. In the first form, which is also the most common, occurs in young male children, usually before they reach the age of twelve. Although this is the most severe form, causing loss of the function of the brain and nervous system, it has the most available treatments. The second form, which is usually present in adults, is characterized by a gradual loss of nerve function, much like that of multiple sclerosis. It has also been misdiagnosed by some inexperienced or uninformed doctors as MS, which may lend some insight as to the similarities between the two diseases. Unfortunately, there are no recognized treatments for this form of the disease. The third form is very similar to Addisons Disease, in which the VLCFA build up in the adrenal glands, and they lose their function. For this form though, there are treatments availa...
